Document Report Card

ID: ALA1145473

Journal: Antimicrob Agents Chemother

Title: Efficacy of the de novo-derived antimicrobial peptide WLBU2 against oral bacteria.

Authors: Novak KF, Diamond WJ, Kirakodu S, Peyyala R, Anderson KW, Montelaro RC, Mietzner TA.

Abstract: The efficacy of a novel synthetic antimicrobial peptide (WLBU2) was evaluated against three oral microorganisms (grown planktonically): Streptococcus gordonii, Fusobacterium nucleatum, and Porphyromonas gingivalis. WLBU2 killed all three species, with F. nucleatum being the most susceptible. WLBU2 also reduced the bacterial burden of S. gordonii and F. nucleatum biofilms.

CiteXplore: 17325219

DOI: 10.1128/aac.00924-06