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ID: ALA1145577
Journal: Bioorg Med Chem Lett
Title: IRAK-4 inhibitors. Part III: a series of imidazo[1,2-a]pyridines.
Authors: Buckley GM, Fosbeary R, Fraser JL, Gowers L, Higueruelo AP, James LA, Jenkins K, Mack SR, Morgan T, Parry DM, Pitt WR, Rausch O, Richard MD, Sabin V.
Abstract: Following the identification of a potent IRAK inhibitor through routine project cross screening, a novel class of IRAK-4 inhibitor was established. The SAR of imidazo[1,2-a]pyridino-pyridines and benzimidazolo-pyridines was explored.
CiteXplore: 18501603