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ID: ALA1145607
Journal: Bioorg Med Chem Lett
Title: Design, synthesis and evaluation of 2-phenyl-1H-benzo[d]imidazole-4,7-diones as vascular smooth muscle cell proliferation inhibitors.
Authors: Ryu CK, Lee RY, Lee SY, Chung HJ, Lee SK, Chung KH.
Abstract: A series of 2-phenyl-1H-benzo[d]imidazole-4,7-diones were synthesized and tested for their inhibitory activity on the PDGF-stimulated proliferation of rat aortic vascular smooth muscle cells. Among the tested compounds, 6-arylthio-5-chloro-2-phenyl-1H-benzo[d]imidazole-4,7-diones exhibited an potent antiproliferative activity.
CiteXplore: 18400498