Document Report Card

ID: ALA1145669

Journal: J Nat Prod

Title: Antihepatotoxic principles of Atractylodes rhizomes.

Authors: Kiso Y, Tohkin M, Hikino H.

Abstract: Extracts of various samples of the crude drug prepared from Atractylodes rhizomes exhibited antihepatotoxic activity by in vitro assay methods using carbon tetrachloride- and galactosamine-induced cytotoxicity in primary cultured rat hepatocytes. The main sesquiterpenoid components were subjected to screening by these methods to reveal that atractylon, beta-eudesmol, and hinesol exerted significant liver-protective effects. Some analogs were also assayed.

CiteXplore: 6418860

DOI: 10.1021/np50029a010