Document Report Card

ID: ALA1145708

Journal: J Nat Prod

Title: Selective cytotoxicity of ginkgetin from Selaginella moellendorffii.

Authors: Sun CM, Syu WJ, Huang YT, Chen CC, Ou JC.

Abstract: Bioassay-directed fractionation of an ethanolic extract of Selaginella moellendorffii has led to the isolation of a known biflavone, ginkgetin (1). A dose-dependent inhibition was observed with 1 on the growth of OVCAR-3 (human ovarian adenocarcinoma) cells with 50% inhibition occurring at 1.8 micrograms/mL. Nonbioactive fractions yielded four additional known biflavones, amentoflavone 7,4',7",4"'-tetramethyl ether, kayaflavone, podocarpusflavone A, and amentoflavone.

CiteXplore: 9134745

DOI: 10.1021/np960608e