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ID: ALA1145732

Journal: Bioorg Med Chem Lett

Title: Non-imidazole heterocyclic histamine H3 receptor antagonists.

Authors: Chai W, Breitenbucher JG, Kwok A, Li X, Wong V, Carruthers NI, Lovenberg TW, Mazur C, Wilson SJ, Axe FU, Jones TK.

Abstract: Continued exploration of the SAR around the lead imidazopyridine histamine H(3) antagonist 1 has led to the discovery of several related series of heterocyclic histamine H(3) antagonists. The synthesis and SAR of indolizine, indole and pyrazolopyridine based compounds are now described.

CiteXplore: 12729661

DOI: 10.1016/s0960-894x(03)00299-3