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ID: ALA1145871
Journal: Bioorg Med Chem Lett
Title: Design and pharmacology of peptoids and peptide-peptoid hybrids based on the melanocortin agonists core tetrapeptide sequence.
Authors: Holder JR, Bauzo RM, Xiang Z, Scott J, Haskell-Luevano C.
Abstract: A series of N-substituted glycine oligomers (peptoids) and peptide-peptoid hybrids were synthesized based on the Ac-His-Phe-Arg-Trp-NH(2) tetrapeptide template. The compounds were pharmacologically characterized at the mouse melanocortin receptors (MC1R, MC3R-MC5R) for agonist activity.
CiteXplore: 14643357