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ID: ALA1146039

Journal: Bioorg Med Chem Lett

Title: Synthesis and antitumor activity of two natural N-acetylglucosamine-bearing triterpenoid saponins: lotoidoside D and E.

Authors: Yan MC, Liu Y, Chen H, Ke Y, Xu QC, Cheng MS.

Abstract: Two natural triterpenoid saponins bearing N-acetylglucosamine, lotoidoside D and lotoidoside E, which had been available only from Glinus lotoides growing in Egyptian desert, were facilely synthesized from readily available oleanolic acid. Preliminary pharmacological research showed their antitumor activity against HeLa cell.

CiteXplore: 16765595

DOI: 10.1016/j.bmcl.2006.05.086