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ID: ALA1146116
Journal: Bioorg Med Chem Lett
Title: N-thiolated 2-oxazolidinones: a new family of antibacterial agents for methicillin-resistant Staphylococcus aureus and Bacillus anthracis.
Authors: Mishra RK, Revell KD, Coates CM, Turos E, Dickey S, Lim DV.
Abstract: In this report, we describe a new family of N-thiolated 2-oxazolidinones having antibacterial activity against methicillin-resistant Staphylococcus aureus and Bacillus anthracis. The effect of ring substituents and stereochemistry on antibacterial activity of these oxazolidinones closely parallels that previously reported for N-thiolated beta-lactam antibiotics.
CiteXplore: 16464583