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ID: ALA1146257

Journal: Bioorg Med Chem Lett

Title: 2,6-Quinolinyl derivatives as potent VLA-4 antagonists.

Authors: Lassoie MA, Broeders F, Collart P, Defrère L, de Laveleye-Defais F, Demaude T, Gassama A, Guillaumet G, Hayez JC, Kiss L, Knerr L, Nicolas JM, Norsikian S, Quéré L, Routier S, Verbois V, Provins L.

Abstract: A new series of 2,6-quinolinyl derivatives was prepared leading to potent low nanomolar VLA-4/VCAM-1 antagonists.

CiteXplore: 17035017

DOI: 10.1016/j.bmcl.2006.09.069