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ID: ALA1146324
Journal: Bioorg Med Chem Lett
Title: Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea).
Authors: Ali A, Bliese M, Rasmussen JA, Sargent RM, Saubern S, Sawutz DG, Wilkie JS, Winkler DA, Winzenberg KN, Woodgate RC.
Abstract: A series of 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives were synthesized and evaluated for in vitro activity against the endoparasite Haemonchus contortus and the ectoparasite Ctenocephalides felis. Some compounds had significant in vitro activity against these parasites.
CiteXplore: 17150358