Immunomodulatory constituents from an Ascomycete, Chaetomium seminudum.

ID: ALA1146466

Journal: J Nat Prod

Title: Immunomodulatory constituents from an Ascomycete, Chaetomium seminudum.

Authors: Fujimoto H, Sumino M, Okuyama E, Ishibashi M.

Abstract: A screening study focusing on immunomodulatory activity of the EtOAc extract of an Ascomycete, Chaetomium seminudum, has afforded a known epipolythiodioxopiperazine, chetomin (1), together with three new chetomin-related metabolites named chetoseminudins A (2), B (3), and C (4). Among these four metabolites, 1 and 2 have been deduced as the immunosuppressive features of this fungus.

CiteXplore: 14738397

DOI: 10.1021/np0302201

Patent ID: ┄