Document Report Card

ID: ALA1146569

Journal: J Nat Prod

Title: The pterocellins, novel bioactive alkaloids from the marine bryozoan Pterocella vesiculosa.

Authors: Yao B, Prinsep MR, Nicholson BK, Gordon DP.

Abstract: Two new alkaloids, pterocellins A and B, have been isolated from the New Zealand marine bryozoan Pterocella vesiculosa. Structural elucidation was achieved through NMR and mass spectral analysis in conjunction with a single-crystal X-ray diffraction study of pterocellin A. The pterocellins possess a novel heterocyclic skeleton and exhibit potent antitumor activity and antimicrobial activity in vitro but only modest activity in the in vivo hollow fiber assay at the National Cancer Institute.

CiteXplore: 12932127

DOI: 10.1021/np030104y