Synthesis and structure-activity relationships of open D-Ring galanthamine analogues.

ID: ALA1146616

Journal: Bioorg Med Chem Lett

Title: Synthesis and structure-activity relationships of open D-Ring galanthamine analogues.

Authors: Herlem D, Martin MT, Thal C, Guillou C.

Abstract: Open D-ring galanthamine analogues were prepared using ring-opening reactions of the quaternarized urethane or oxazolidine functions and were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibition potency.

CiteXplore: 12824041

DOI: 10.1016/s0960-894x(03)00397-4

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