Document Report Card
Basic Information
ID: ALA1146660
Journal: Bioorg Med Chem Lett
Title: Design and synthesis of dysidiolide analogs from vitamin D3: novel class of Cdc25A inhibitors.
Authors: Shimazawa R, Suzuki T, Dodo K, Shirai R.
Abstract: Potent dysidiolide analogs were synthesized by structural hybridization of dysidiolide and vitamin D(3). These analogs exhibited strong inhibitory activity toward dual-specificity phosphatase Cdc25A (IC(50)=0.44-0.89 microM).
CiteXplore: 15149692