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ID: ALA1146723

Journal: Bioorg Med Chem Lett

Title: Synthesis of benzophenone oxime analogues as inhibitor of secretory phospholipase A(2) with anti-inflammatory activity.

Authors: Murari SK, Sriharsha SN, Shashikanth S, Vishwanath BS.

Abstract: The title compound have been synthesized and tested for structure activity relationship for Phospholipase A(2) (PLA(2)) [E.C. 3.1.1.4] enzyme inhibition. The in vitro PLA(2) enzyme inhibitory activity of benzophenone oxime analogue and in vivo anti-inflammatory activity studies using mice are highlighted.

CiteXplore: 15109625

DOI: 10.1016/j.bmcl.2004.03.019