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ID: ALA1146749
Journal: Bioorg Med Chem Lett
Title: The effect of C2-fluoro group on the biological activity of DC-81 and its dimers.
Authors: Kamal A, Reddy PS, Reddy DR.
Abstract: C2-Fluoro substituted pyrrolobenzodiazepines (PBDs) have been synthesized that exhibit potential anticancer activity in a number of human tumour cell lines. These C2-fluoro substituted PBDs also exhibit significant DNA-binding ability.
CiteXplore: 15109675