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ID: ALA1146781
Journal: Bioorg Med Chem Lett
Title: Structural differences between paroxetine and femoxetine responsible for differential inhibition of Staphylococcus aureus efflux pumps.
Authors: Wei P, Kaatz GW, Kerns RJ.
Abstract: In this study the chemical modification of paroxetine was employed to determine which structural differences between the paroxetine-like and femoxetine-like selective serotonin reuptake inhibitors is responsible for the differential potency of these agents in the inhibition of Staphylococcus aureus multidrug efflux pump systems.
CiteXplore: 15149651