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ID: ALA1146819

Journal: Bioorg Med Chem Lett

Title: Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta.

Authors: Gong B, Hong F, Kohm C, Bonham L, Klein P.

Abstract: 2-Arylbenzoxazoles, benzothiazoles and benzimidazoles were identified as new classes of potent, isoform specific inhibitors of lysophosphatidic acid acyltransferase-beta (LPAAT-beta). Effects of selected inhibitors on proliferation of tumor cells in vitro were investigated.

CiteXplore: 15006381

DOI: 10.1016/j.bmcl.2004.01.023