A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions.

Basic Information

ID: ALA1146932

Journal: Bioorg Med Chem Lett

Title: A series of 23,24-dihydrodiscodermolide analogues with simplified lactone regions.

Authors: Shaw SJ, Sundermann KF, Burlingame MA, Zhang D, Petryka J, Myles DC.

Abstract: A collection of seven new 23,24-dihydrodiscodermolide analogues have been synthesized with modifications to the lactone ring, some of which show antiproliferative activities similar to discodermolide.

CiteXplore: 16413186

DOI: 10.1016/j.bmcl.2005.12.066

Patent ID: