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ID: ALA1146968

Journal: Bioorg Med Chem Lett

Title: Novel skeleton terpenes from Celastrus hypoleucus with anti-tumor activities.

Authors: Wang KW, Mao JS, Tai YP, Pan YJ.

Abstract: Celahypodiol 1, an unusual 17-membered carbon diterpenoid with a novel skeleton, and a new triterpenoid 12-oleanene-3beta,6alpha-diol 2, together with four known compounds furreginol 3, suigol 4, 20(30)-lupene-3beta, 29-diol 5, and 20(29)-lupene-1beta,3beta-diol 6, were isolated from the stalks of Celastrus hypoleucus (Oliv.) Warb. Their structures were established by means of spectroscopic analysis, including 2D NMR. The new compounds exhibited anti-tumor activities against a panel of human tumor cell lines.

CiteXplore: 16455245

DOI: 10.1016/j.bmcl.2006.01.021