Document Report Card

ID: ALA1147218

Journal: J Nat Prod

Title: New bioactive diterpene polyesters from Euphorbia decipiens.

Authors: Ahmad VU, Hussain H, Jassbi AR, Hussain J, Bukhari IA, Yasin A, Aziz N, Choudhary MI.

Abstract: A reinvestigation with a modified extraction procedure of Euphorbia decipiens resulted in the isolation and structure elucidation of three new myrsinane-type diterpene esters (1-3). The structures of compounds 1-3 were elucidated by spectroscopic data interpretation. Compound 1 showed inhibitory activity against prolyl endopeptidase (PEP), whereas compound 2 exhibited DNA-damaging activity in a mutant yeast bioassay.

CiteXplore: 14510601

DOI: 10.1021/np020186a