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ID: ALA1147288

Journal: J Nat Prod

Title: Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin.

Authors: Van Puyvelde L, De Kimpe N, Costa J, Munyjabo V, Nyirankuliza S, Hakizamungu E, Schamp N.

Abstract: 3,5-Dihydroxy-6,7,8-trimethoxyflavone, 3-O-methylquercetin, and helichrysetin were isolated from the flowers of the Rwandese medicinal plant, Helichrysum odoratissimum. Because of inconsistencies of the mp of the latter chalcone, a synthesis of helichrysetin was developed. 3-O-Methylquercetin was shown to be an active principle as it displayed antimicrobial activity.

CiteXplore: 2778452

DOI: 10.1021/np50063a025