Document Report Card

ID: ALA1147301

Journal: J Nat Prod

Title: Studies on inhibitors of skin-tumor promotion. Inhibitory effects of triterpenes from Cochlospermum tinctorium on Epstein-Barr virus activation.

Authors: Diallo B, Vanhaelen M, Vanhaelen-Fastré R, Konoshima T, Kozuka M, Tokuda H.

Abstract: Arjunolic acid, an oleanene-type triterpene isolated from the rhizome of Cochlospermum tinctorium, its triacetate derivative, and their methyl esters were tested using the short-term in vitro assay on EBV-EA activation in Raji cells induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA). Their inhibitory effects on skin tumor promotors were found to be greater than those of previously studied natural products.

CiteXplore: 2553872

DOI: 10.1021/np50064a039