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ID: ALA1147402
Journal: Bioorg Med Chem Lett
Title: Synthesis and antitumour activity of pyrene-linked pyrrolo [2,1-c]benzodiazepine hybrids.
Authors: Kamal A, Ramesh G, Srinivas O, Ramulu P.
Abstract: Pyrene-linked pyrrolobenzodiazepine hybrids have been synthesized that exhibit potential anticancer activity in a number of human tumour cell lines. These hybrids also exhibit much enhanced DNA-binding ability in comparison to the parent pyrrolobenzodiazepine ring system (DC-81).
CiteXplore: 14698184