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ID: ALA1147420
Journal: Bioorg Med Chem Lett
Title: Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage.
Authors: Kontogiorgis CA, Hadjipavlou-Litina DJ.
Abstract: The synthesis of several novel coumarin derivatives with a 7-azomethine linkage was carried out starting from 7-formyl-coumarin. The compounds were tested in vivo for their anti-inflammatory activity and in vitro for their antioxidant ability. Compounds 3a and 3e possess significant protection against carrageenin induced rat paw edema.
CiteXplore: 14741253