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ID: ALA1147559
Journal: Bioorg Med Chem Lett
Title: Synthesis and antitumor evaluation of benzoylphenylurea analogs.
Authors: Gurulingappa H, Amador ML, Zhao M, Rudek MA, Hidalgo M, Khan SR.
Abstract: Novel series of benzoylphenylurea analogs 7-10 were prepared and evaluated for in vitro cytotoxic activity against a panel of eight different human cancer cell lines. A very interesting inhibition profile against BxPC3, Mia-Paca, and Hep2 cells with compound 10 has been observed. Compounds 8 and 9 showed the significant cytotoxicity in Hep2 cells. All cell lines were resistant to compound 7.
CiteXplore: 15081011