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ID: ALA1147691
Journal: Bioorg Med Chem Lett
Title: Quinol fatty alcohols as promoters of axonal growth.
Authors: Hanbali M, Vela-Ruiz M, Bagnard D, Luu B.
Abstract: The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n=15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.
CiteXplore: 16517160