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ID: ALA1147772
Journal: Bioorg Med Chem Lett
Title: The identification of potent and selective imidazole-based inhibitors of B-Raf kinase.
Authors: Takle AK, Brown MJ, Davies S, Dean DK, Francis G, Gaiba A, Hird AW, King FD, Lovell PJ, Naylor A, Reith AD, Steadman JG, Wilson DM.
Abstract: A novel triarylimidazole derivative, SB-590885 (33), bearing a 2,3-dihydro-1H-inden-1-one oxime substituent has been identified as a potent and extremely selective inhibitor of B-Raf kinase.
CiteXplore: 16260133