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ID: ALA1147913

Journal: Bioorg Med Chem

Title: Na+-glucose cotransporter (SGLT) inhibitory flavonoids from the roots of Sophora flavescens.

Authors: Sato S, Takeo J, Aoyama C, Kawahara H.

Abstract: The methanol extract of Sophora flavescens, which is used in traditional Chinese medicine (sophorae radix), showed potent Na(+)-glucose cotransporter (SGLT) inhibitory activity. Our search for active components identified many well-known flavonoid antioxidants: kurarinone, sophoraflavanone G, kushenol K, and kushenol N.

CiteXplore: 17374486

DOI: 10.1016/j.bmc.2007.03.011