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ID: ALA1147927

Journal: Bioorg Med Chem Lett

Title: Piperazinyl CCR1 antagonists--optimization of human liver microsome stability.

Authors: Brown MF, Bahnck KB, Blumberg LC, Brissette WH, Burrell SA, Driscoll JP, Fedeles F, Fisher MB, Foti RS, Gladue RP, Guzman-Martinez A, Hayward MM, Lira PD, Lillie BM, Lu Y, Lundquist GD, McElroy EB, McGlynn MA, Paradis TJ, Poss CS, Roache JH, Shavnya A, Shepard RM, Trevena KA, Tylaska LA.

Abstract: The synthesis, biological activity, and pharmacokinetic profile of CCR1 antagonists are described.

CiteXplore: 17383873

DOI: 10.1016/j.bmcl.2007.03.037