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Ophirapstanol trisulfate, a new biologically active steroid sulfate from the deep water marine sponge Topsentia ophiraphidites.

Basic Information

ID: ALA1148096

Journal: J Nat Prod

Title: Ophirapstanol trisulfate, a new biologically active steroid sulfate from the deep water marine sponge Topsentia ophiraphidites.

Authors: Gunasekera SP, Sennett SH, Kelly-Borges M, Bryant RW.

Abstract: Ophirapstanol trisulfate [1], a new steroid trisulfate related to sokotrasterol trisulfate was isolated from a deep water marine sponge Topsentia ophiraphidites. Compound 1 exhibited significant inhibition in the guanosine diphosphate/G-protein RAS exchange assay. The structure elucidation of 1 and ophirapstanol [2] by nmr spectroscopy is described.

CiteXplore: 7714543

DOI: 10.1021/np50114a024

Patent ID: