Document Report Card

ID: ALA1148127

Journal: J Nat Prod

Title: Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline.

Authors: Kariba RM, Houghton PJ, Yenesew A.

Abstract: Extracts from Schizozygia coffaeoides showed antimicrobial activity against fungal and bacterial species. Alkaloids isolated using bioassay-guided fractionation were isoschizogaline, schizogynine, and a new indoline alkaloid, 7,8-dehydro-19beta-hydroxyschizozygine, shown to be the most active antifungal compound. The structure of isoschizagaline, the only active antibacterial, is revised on the basis of NMR analysis.

CiteXplore: 11975502

DOI: 10.1021/np010298m