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ID: ALA1148247

Journal: Bioorg Med Chem Lett

Title: Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand.

Authors: Nishino N, Yoshikawa D, Watanabe LA, Kato T, Jose B, Komatsu Y, Sumida Y, Yoshida M.

Abstract: Cyclic tetrapeptide retrohydroxamic acids were prepared as histone deacetylase (HDAC) inhibitors and evaluated the inhibitory activity and found that they have potential as anticancer drugs.

CiteXplore: 15109626

DOI: 10.1016/j.bmcl.2004.03.018