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ID: ALA1148258
Journal: Bioorg Med Chem Lett
Title: Synthesis of OSW-1 analogs with modified side chains and their antitumor activities.
Authors: Deng L, Wu H, Yu B, Jiang M, Wu J.
Abstract: Four analogs of OSW-1 (1-4) with modified side chains on the steroidal skeleton were synthesized following modification of our previous route for the total synthesis of OSW-1. Testing of the analogs against growth of tumor cells demonstrated that the 22-one function and the full length of the side chain of OSW-1 were not required for the antitumor action of OSW-1.
CiteXplore: 15125932