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ID: ALA1148271

Journal: Bioorg Med Chem Lett

Title: 3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT(1B/1D) ligands.

Authors: Egle I, MacLean N, Demchyshyn L, Edwards L, Slassi A, Tehim A.

Abstract: A series of 3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives (2) has been prepared using parallel synthesis techniques, and their structure-activity relationships studied. High affinity human 5-HT(1B/1D) (h5-HT(1B/1D)) ligands have been identified.

CiteXplore: 14741277

DOI: 10.1016/j.bmcl.2003.11.023