Document Report Card

ID: ALA1148302

Journal: J Med Chem

Title: Discovery of diarylacrylonitriles as a novel series of small molecule sortase A inhibitors.

Authors: Oh KB, Kim SH, Lee J, Cho WJ, Lee T, Kim S.

Abstract: On the basis of a hit from random screening, a novel class of small-molecule sortase A inhibitors was generated. The primary structure-activity relationship and the minimal structural requirements for potency were established through structural modifications and molecular modeling studies.

CiteXplore: 15115384

DOI: 10.1021/jm0498708