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ID: ALA1148833
Journal: Bioorg Med Chem Lett
Title: 3-Hydroxychromones as cyclin-dependent kinase inhibitors: synthesis and biological evaluation.
Authors: Lee J, Park T, Jeong S, Kim KH, Hong C.
Abstract: A novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiazolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDAMB468 cancer cells.
CiteXplore: 17178224