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ID: ALA1148912

Journal: J Nat Prod

Title: New diterpenoids from the marine mangrove Bruguiera gymnorrhiza.

Authors: Han L, Huang X, Sattler I, Dahse HM, Fu H, Lin W, Grabley S.

Abstract: Phytochemical investigation of the stem of Bruguiera gymnorrhiza yielded three new ent-kaurane diterpenoids (1, 2, and 3) and one new ent-beyerane diterpenoid (4) together with nine known ent-kaurane diterpenoids. All structures and the relative stereochemistry of the new compounds were determined by NMR spectroscopic studies. The absolute stereochemistry of 4 was determined by CD data. Some of the compounds showed moderate cytotoxic properties.

CiteXplore: 15387677

DOI: 10.1021/np040062t