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ID: ALA1149197
Journal: Bioorg Med Chem Lett
Title: Design and synthesis of beta-amino-alpha-hydroxy amide derivatives as inhibitors of MetAP2 and HUVEC growth.
Authors: Sendzik M, Janc JW, Cabuslay R, Honigberg L, Mackman RL, Magill C, Squires N, Waldeck N.
Abstract: The rational design and synthesis of beta-amino-alpha-hydroxy amide derivatives as reversible inhibitors of methionine aminopeptidase-2 (MetAP2) with anti-proliferative activity against human umbilical vein endothelial cells (HUVECs) is described.
CiteXplore: 15149671