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ID: ALA1149205

Journal: Bioorg Med Chem Lett

Title: Biological evaluation of substituted quinolines.

Authors: Franck X, Fournet A, Prina E, Mahieux R, Hocquemiller R, Figadère B.

Abstract: Several quinolines were synthesized and evaluated in vitro against several parasites (Trypanosoma brucei, T. cruzi, Leishmania infantum, L. amazonensis, Plasmodium falciparum). Then, they were evaluated in vitro (at 10 microM), against HTLV-1 transformed cells. A few of them displayed interesting activities, comparable to the reference drugs.

CiteXplore: 15203133

DOI: 10.1016/j.bmcl.2004.05.026