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ID: ALA1149355

Journal: Bioorg Med Chem Lett

Title: Structure-activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5).

Authors: Bach P, Nilsson K, Svensson T, Bauer U, Hammerland LG, Peterson A, Wållberg A, Osterlund K, Karis D, Boije M, Wensbo D.

Abstract: Studies of structure-activity relationships for the linker in a new series of metabotropic glutamate receptor 5 antagonists are presented together with in vitro and in vivo pharmacokinetic data.

CiteXplore: 16837196

DOI: 10.1016/j.bmcl.2006.06.078