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ID: ALA1149417

Journal: Bioorg Med Chem Lett

Title: Androstenediol analogs as ER-beta-selective SERMs.

Authors: Blizzard TA, Gude C, Morgan JD, Chan W, Birzin ET, Mojena M, Tudela C, Chen F, Knecht K, Su Q, Kraker B, Mosley RT, Holmes MA, Sharma N, Fitzgerald PM, Rohrer SP, Hammond ML.

Abstract: A series of 19-substituted androstenediol derivatives was prepared. Some of the novel analogs were surprisingly potent and selective ligands for ER-beta.

CiteXplore: 16309907

DOI: 10.1016/j.bmcl.2005.11.014