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ID: ALA1149541

Journal: Bioorg Med Chem Lett

Title: Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids.

Authors: Marsault E, Benakli K, Beaubien S, Saint-Louis C, Déziel R, Fraser G.

Abstract: Novel, potent small molecule motilin receptor antagonists are described. These peptidomimetic macrocycles are composed of a tripeptide cyclized backbone-to-backbone with a nonpeptidic tether and bear new unnatural amino acids containing basic side chains.

CiteXplore: 17533127

DOI: 10.1016/j.bmcl.2007.05.043