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ID: ALA1149612

Journal: Bioorg Med Chem

Title: Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres.

Authors: Liger F, Popowycz F, Besson T, Picot L, Galmarini CM, Joseph B.

Abstract: Aza-analogues of clausine E, mukonine and koenoline were prepared from 1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde and their antiproliferative activity was evaluated against miscellaneous cancer cell lines and compared to those obtained with clausine E and mukonine.

CiteXplore: 17548198

DOI: 10.1016/j.bmc.2007.05.033