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ID: ALA1149702
Journal: Bioorg Med Chem Lett
Title: Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.
Authors: Mugnaini C, Rajamaki S, Tintori C, Corelli F, Massa S, Witvrouw M, Debyser Z, Veljkovic V, Botta M.
Abstract: The identification of a novel hit compound as integrase binding inhibitor has been accomplished by means of virtual screening techniques. A small family of structurally related molecules has been synthesized and biologically evaluated with one of the compounds showing an IC(50)=12 microM.
CiteXplore: 17716893