Document Report Card

ID: ALA1149879

Journal: J Nat Prod

Title: Ten-membered lactones from Phomopsis sp., an endophytic fungus of Azadirachta indica.

Authors: Wu SH, Chen YW, Shao SC, Wang LD, Li ZY, Yang LY, Li SL, Huang R.

Abstract: Four new 10-membered lactones ( 1- 4) and one known one ( 5) were isolated from the broth extract of an endophytic fungus, Phomopsis sp., obtained from the stem of Azadirachta indica. Their structures were assigned by analysis of spectroscopic data, and the structures of 1 and 4 were also confirmed by X-ray analysis. Compounds 1- 5 were tested for antifungal activity against several plant pathogens. Compound 4 demonstrated antifungal activity in the MIC value range 31.25-500 microg/mL.

CiteXplore: 18336005

DOI: 10.1021/np070624j