Document Report Card

ID: ALA1150075

Journal: J Nat Prod

Title: Apiosporamide, a new antifungal agent from the coprophilous fungus Apiospora montagnei.

Authors: Alfatafta AA, Gloer JB, Scott JA, Malloch D.

Abstract: Bioassay-guided fractionation of an EtOAc extract from the mycelium of the coprophilous fungus Apiospora montagnei has furnished a new antifungal metabolite, named apiosporamide [1], and the known dihydroisocoumarin cis-(3R,4R)-4-hydroxymellein [4]. The structure of 1 was assigned on the basis of HMBC, HMQC, NOESY, and hrms data. Elucidation of the structure was complicated by the fact that several nmr signals appeared only under certain conditions.

CiteXplore: 7714537

DOI: 10.1021/np50114a012