Document Report Card

ID: ALA1150105

Journal: J Nat Prod

Title: Polytolypin, a new antifungal triterpenoid from the coprophilous fungus Polytolypa hystricis.

Authors: Gamble WR, Gloer JB, Scott JA, Malloch D.

Abstract: Polytolypin [1], a new pentacyclic triterpenoid exhibiting antifungal and antibiotic activity, has been isolated from cultures of Polytolypa hystricis (JS189), a fungal colonist of porcupine dung. Two known compounds [2 and 3] were also isolated. Polytolypin was obtained by chromatographic fractionation of the EtOAc extract of P. hystricis liquid cultures, and the structure was assigned on the basis of 2D nmr and hrms data.

CiteXplore: 8691217

DOI: 10.1021/np50126a034