Document Report Card

ID: ALA1150155

Journal: J Nat Prod

Title: Purealidin S and purpuramine J, bromotyrosine alkaloids from the Fijian marine sponge Druinella sp.

Authors: Tabudravu JN, Jaspars M.

Abstract: Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.

CiteXplore: 12502317

DOI: 10.1021/np020275n